The show was produced by the anime studio Madhouse and was directed by Shin Itagaki. Bingo Morihashi, one of the writers for the second, third and fourth games, was also on the writing staff.
A teaser-trailer, released on the show's official site, featured pre-production artwork of Dante, the primary protagonist and playable character of the video games, and confirmed him as the show's main protagonist.
A second trailer released at the 2007 Tokyo International Anime Fair showed actual animation from the show and included a character and cast list, featuring both new characters and other characters from the games.